Folic Acid in Pregnancy Associated With Reduced Risk of Autism in Offspring

Women with low folic acid intake during a window from three months before conception to three months who were exposed to agricultural pesticides thereafter additionally were at higher evaluated risk.

It would be better for women to avoid chronic pesticide exposure. Researchers say during pregnancy mothers who take the prescribed amounts of folic acid may decrease the risk of their kids developing pesticide related autism.

The discoveries demonstrated that if the mother was taking folic acid during the window around conception, the risk related with pesticides appeared to be attenuated.

Lead author Rebecca J said, “Folic acid intake below the median and exposure to pesticides was related to higher risk of autism than either low intake or exposure alone”.

Schmidt, Assistant Professor at the University of California-Davis.Folate plays a critical role in DNA methylation a process by which genes are turned off or on, and in addition to DNA repair and synthesis.

Schmidt added, “These are all really important during periods of rapid growth when there are lots of cells dividing, as in a developing foetus. Adding folic acid may assist in some of these genomic functions”.

In the examination, appearing in the journal Environmental Health Perspectives, the group looked at 296 children aged between 2 and 5 who had been diagnosed with ASD and 220 who had developed typically.

Mothers who took under 400 micrograms and experienced household pesticides had a considerably higher estimated risk of having a child who developed autism than mothers who took 400 to 800 micrograms of folic acid and were not exposed to pesticides. The associated risk increased for women exposed more than once.

Women with low folic acid intake who were exposed to agricultural pesticides during a window from three months before conception to three months afterward additionally were at higher estimated risk.

Schmidt added, while folic acid reduced the related risk of a child developing autism, it didn’t altogether kill it. Along these lines “it would be better for women to stay away from chronic pesticide exposure if they can while pregnant”.

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