New research has found that HPV-inoculated women may just need three smear tests in their lifetimes. Statistical modelling demonstrated a limited advantage to additional screening tests in women who received the HPV-16/18 vaccine as children.
The research carried out by scientists at the Queen Mary University of London, utilized statistical modeling scenarios to determine how many cervical screening tests would be required by women who received the HPV immunization at 12 years old.
They found that the individuals who received the vaccine would just need three smear tests in their lifetimes, with screening tests at ages 30, 40 and 55 preventing an additional 2.8% of cervical cancers. Including a fourth screen prevented only 1% of additional cancers, with additional screens after preventing less than 1%.
They likewise noticed that the screening interval for unvaccinated women could be safely lengthened, finding that this patient group would require only seven smear tests in their lifetime. The outcomes come in front of planned changes to cervical screening in the UK, which will see HPV testing in cervical specimens to screen those in danger of cervical screening in the UK, which will see HPV testing in cervical samples to screen those at risk of cervical cancer being rolled out in England by 2019.
The authors said in the paper: ‘Our outcomes confirm that even in unvaccinated women, screening intervals can be safely lengthened with the introduction of HPV testing with cytology triage, compared with cytology testing.’
Public Health England expressed concern before this over a week over declining figures for cervical cancer screening uptake, which fell by 0.72% overall eligible group in 2016/17.